Freie Universität Berlin
Excellence university with internationally recognized strengths in humanities, social sciences, life sciences, and natural sciences. Strong interdisciplinary research in biodiversity, climate change, and high-performance technologies.
199
Patents
462
Inventors
151
Spin-offs
-
Licensing Deals
Analysis of our organization's intellectual property assets
Total Patents
199
Recent Patent Publications (2025 & 2026)
13
Top Inventors
Patent Portfolio
Discover our latest patented technologies
The present invention relates to a conjugation product comprising an antigen binding moiety and a mucin binding moiety covalently bound to the antigen binding moiety. Due to the mucin binding moiety, the antigen binding efficacy of the antigen binding moiety is significantly increased.
The present invention relates to a coating substance (1, 7, 11), comprising: a polymeric core (2); a positively charged moiety (4) or a negatively charged moiety (4) forming part of the polymeric core (2) or being covalently bound to the polymeric core (2) either directly or via a first linker (3); and a surface-binding moiety (5) covalently bound to the polymeric core (2) either directly or via a second linker (3'); wherein the polymeric core (2) comprises a polymer chosen from the group consisting of hyperbranched polyglycerol, hyperbranched polyglycerol derivatives, polyethyleneimine, polyethyleneimine derivatives, polyallylamine, and polyallylamine derivatives; wherein the positively charged moiety (4) is chosen from amines, quaternary ammonium substituents, and amino groups; wherein the negatively charged moiety (4) is chosen from sulfate groups, sulfonate groups, carboxyl groups, phosphate groups, and phosphonate groups; wherein the first linker (3) and the second linker (3') are chemically identical and are a C4 to C16 alkyl residue; and wherein the surface-binding moiety (5) is chosen from a benzophenone residue and a catechol group.
In one aspect, the disclosure relates to compounds and pharmaceutical compositions for treating diseases or disorders associated with aberrant Kifc3 function in a subject. In a further aspect, the disease or disorder can be selected from neonatal thrombocytopenia, delayed platelet recovery following umbilical cord blood stem cell transplantation, Down syndrome-associated myeloid neoplasm, or any combination thereof. In one aspect, the subject can be a human, including a neonatal human, and performing the method increases platelet production in the subject. Also disclosed are methods for ex vivo platelet production using the disclosed compounds and pharmaceutical compositions.
Success Stories
Companies founded based on our organization's technologies
AVALY GmbH offers data-driven, AI-powered software to help energy and infrastructure developers manage local social acceptance for projects such as wind and solar farms.
Caidera GmbH is an AI-driven compliance platform for life sciences marketing, enabling faster and compliant content creation for regulated industries such as pharma, medtech, and biotech.
The Freie Universität Berlin Technology Transfer team is ready to assist you with licensing inquiries and collaboration opportunities
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